Hiring company: BMS
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Juno Therapeutics GmbH Munich is seeking a Manufacturing Specialist to support the development of engineered T-cell products. The team is responsible for transferring manufacturing technologies for the development of gene-engineered T cells to a GMP-compliant environment. Successful candidates will have a strong foundation in aseptic manufacturing of primary human cells in compliance with GMP regulations.
Your responsibilities will include but are not limited to:
- Work with Process Development and other teams to develop and transfer next generation cell manufacturing processes to internal and external GMP facilities
- Aseptic production of cell-based products in clean rooms in compliance with manufacturing instructions and according to relevant hygiene and GMP regulations
- Perform cell selection, cell culture, viral and non-viral gene transfer, and cryopreservation
- Support in evaluation and implementation of process optimization and provide guidance and troubleshooting assistance as needed during a deviation in the process
- Monitoring and qualification of clean room and equipment
- Support warehouse management and coordinate supply inventory
- May train peers and other manufacturing employees in manufacturing process
- Authoring and execution of SOPs and batch records
- Documentation and analysis of data
Required qualifications:
- Educated as BTA / PTA / MTA / CTA or BSc in Biology, biotechnology, bioengineering or medical technology related field with a minimum of three years’ experience in aseptic manufacturing of human cell products.
- Strong knowledge of sterile cell culture lab techniques such as cell passaging, cryopreservation, and formulation of media is mandatory
- Cell therapy manufacturing experience in a GMP-regulated environment is preferred
- Experience with common cell processing devices such as CliniMACS, closed system cell washer, bioreactors and controlled-rate freezers is a plus
- Experience with working in a clean room with full aseptic gowning is beneficial
- High understanding of quality and responsibility
- Ability to work independently and in a team setting
- Fluent in German and good English skills are required (oral and written)
- Computer literacy including Microsoft Outlook, Word, Excel, and PowerPoint
Desirable Qualifications:
- Experience in flow cytometry and immunological in vitro assays such as ELISA and ELISpot
Willingness to learn new analytical methodologies
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.