Principal Scientist– Translational Pathology and Immunohistochemistry, Translational Sciences and Diagnostics, Translational Medicine

  • Full time
  • Princeton - NJ - US

Hiring company: BMS

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Translational Pathology and Immunohistochemistry Group is seeking a highly-motivated Senior Research Investigator with a background in cancer biology, immunology or related disciplines in the medical and biological sciences and experience in monoplex and multiplex immunohistochemistry assay development and implementation.

We are a team of pathologists and scientists who integrate tissue-based data into clinical insights that enable the delivery of therapies to the patients most likely to benefit from them. Members of this team work on various projects in close collaboration with teams supporting early and late clinical development. The focus of this role is on the design, development and implementation of translational tissue-based biomarker assays to interrogate drug mechanism of action, to better understand mechanisms of disease and therapeutic resistance, ­­and to predict likelihood of response to treatment. The successful candidate will work with colleagues throughout BMS on IHC and other tissue-based assays for internal use and will be also accountable for assay transfer and refinement with external partners. The scientist will also be responsible for working with colleagues from digital pathology to assess assay suitability and endpoints for digital image analysis. The successful candidate will be a highly motivated and collaborative individual with the ability to multitask and drive team achievement while working across multiple disciplines in a complex matrix organization. Excellent written and verbal communication skills and the ability to clearly communicate scientific objectives and analyze and interpret data are required.

Qualifications:

  • Extensive knowledge of IHC principles and instrumentation
  • A minimum of 5 years of relevant work experience
  • Experience in monoplex and multiplex IHC (brightfield and fluorescence-based) assay development and IHC stains in tissues
  • Experience with in-situ nucleic acid hybridization (RNA/DNA) studies on tissue samples is a plus, as is a working knowledge of basic histomorphology and pathology
  • An advanced degree (MS or PhD) in Biological Sciences or related Biomedical fields is preferred, as is a clear demonstration of high-quality scholarly productivity in a relevant field of biomedical research
  • Prior experience working in the fields of oncology and immuno-oncology is preferred
  • Prior experience working in a regulated laboratory setting (CAP/CLIA or other GxP environment) is desirable
  • Experience with digital image analysis (HALO, ImageJ, Visiopharm, Inform, etc.) of whole-slide histologic and immunohistochemical sections is highly desirable
  • Collaborative/team spirit and ability to thrive in a matrixed environment
  • Self-motivated and eager to learn new skills and technologies

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. 

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.  Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.  This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

    Get Notified for Similar Jobs
    Sign up to receive job alerts